Autoimmune inflammatory syndrome induced by adjuvants (ASIA) was first described in 2011 by Yehuda Shoenfeld and Nancy Agmon-Levin as a condition characterized by an autoimmune response in humans after exposure to an adjuvant.1 Adjuvants enhance the immune response, but they do not act on their own; they help produce a more relevant reaction against the inoculated antigens. There were 98.4% female patients, and the mean patient age was 41 10.3 years. The data show a standard deviation of 0.3. Human adjuvant-related syndrome or autoimmune/inflammatory syndrome induced by adjuvants. In both cases the paraclinical results were considered. Direct Contact for WhatsApp It is important to read the study in the context of the population studied when extrapolating the information. The suspension was gently stirred for 1h on a magnetic stirrer in order to achieve a uniform dispersion of the clay particles. This is done to improve the moisture loss of the plant, increasing the contact surface with the atmosphere (Figure9). Patient may return to working activities fifteen days after surgery depending on recovery of each patient and kind of working activity that they have. Evidence refuting the existence of autoimmune/autoinflammatory syndrome induced by adjuvants (ASIA). However, some patients may develop similar pathologies despite an adequate removal technique as it is not possible to remove the entire product. a. Pre-surgical photograph of a 45-year-old woman with a 10-year history. The prevalence of ASIA period found in this cohort between January 1, 2017 and December 31, 2020 is 5.3%, which is calculated taking into account as numerator 190 patients with the diagnosis and as denominator 3550 patients seen in the clinic with any diagnosis or procedure during the same period in the clinic, and the prevalence of ASIA period calculated for patients with biopolymer injection is 4.8% taking into account as numerator 171 cases and the same denominator reported above. Brief introduction to this section that descibes Open Access especially from an IntechOpen perspective, Want to get in touch? Cutting of thorns and removal of the bark: To perform the extraction of the coagulant, the cut parts are taken and the thorns are removed (Figure8), and the skin of the cacti, also called epidermis, which is the external hard part of the pads or cladodes, in the case of cactus and leaves in the case of Aloe species. Click on each profile to know all the services offered including the Biopolymer Removal. MedicosDoc.com | Barranquilla, Colombia | Tel: 305 337 7860, Doctors Barranquilla | Doctors Cartagena | Doctors Cali | Doctors Santa Marta | Doctors Bogot, Outpatient consultation in general medicine, Resections of tumors of the parotid mouth and larynx, Artificial insemination. Watad A, Quaresma M, Bragazzi NL, et al. This study found that the mean time that biopolymers take to produce symptoms after their administration is 10.4 4 years and that patients showed elevated levels of ANA, LDH, complement proteins C3 and C4, and rheumatoid factor preoperatively. Then it consists of applying energy by means of ultrasound or laser to break the scar covering the biopolymers in order to remove them by means of suction. At Colombian Curves we bridge the gap between renown plastic surgeons and clients, making your experience nearly convenient. 1993:19. Cheeks and cheekbones if injected into the face, hips, back, thighs and calves if placed in buttocks. The plants described in this chapter are Melocactus sp., Opuntia sp., Stenocereus griseus, Cereus forbesii, Aloe arborescens, Aloe vera, and Kabuli chickpea (Cicer arietinum L.), of these plants have been used different parts, either their stems, their fruits, or other parts of the plant that have demonstrated a coagulating or flocculating capacity. 48 No. ASIA syndrome symptoms induced by gluteal biopolymer injections: Case-series and narrative review Toxicol Rep. 2021 Jan 27;8:303-314. doi: 10.1016/j . Thus, alternatives such as buttock prostheses and lipo-injection are supplementary mechanisms for this loss of volume. 99 - 51, local LM 002 B. Placing prosthesis or fat must be done at least six months after removing biopolymers. To have a better selection, we reviewed the massive presence of these plants and that they were not part of the list of plants in danger of extinction, to be able to access their manipulation. Barranquilla, Colombia, Facial rejuvenation, botulinum toxin, hyaluronic acid, Laser hair removal, Serotherapy, Calle 134 No. Copyright HDEstheque 2020 All rights reserved. Bogot, Colombia, $230,000 fee for serviceVIEW PROFILE$230,000 fee for serviceVirtual Guidance, Facial plastic surgery, Rhinoplasty, Rhinomodelation, Blepharoplasty, Botulinum toxin, Facial fillers, Calle 86 No. The results of the tests of the biopolymers, natural coagulants, are collected in four main tests, the first ones refer to the pH, the turbidity, and the color; the last one takes the coagulants with good performance and measures the Z potential. Silicone injections can often introduce dangerous foreign substances to the inside of the body. The extractions of each plant have particularities, taking into account the usable parts in the search of their coagulating capacity. Revista Colombiana de Ciruga Plstica y Reconstructiva. The focus of our work is a Safe Patient Culture, which, beyond a service philosophy, is our drive, it is our habit. Plastic and Reconstructive Surgery - Global Open, Get new journal Tables of Contents sent right to your email inbox, Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), https://www.elsevier.com/es-es/connect/medicina/asia,-el-extrano-sindrome-inducido-por-adyuvantes, https://www.minsalud.gov.co/sites/rid/Lists/, BibliotecaDigital/RIDE/DE/DIJ/RESOLUCION-8430-DE-1993.PDF, Clinical and Immunological Characteristics of Patients with Biopolymers and Autoimmune Inflammatory Syndrome Induced by Adjuvants, Articles in PubMed by Jaime Eduardo Pachn S, MD, Articles in Google Scholar by Jaime Eduardo Pachn S, MD, Other articles in this journal by Jaime Eduardo Pachn S, MD, A Safe and Effective Lip Augmentation Method: The Step-by-Step (Phi) Technique, Complicated Facial Fillers: Management Algorithm, Consensus Recommendations for Treatment Strategies in Indians Using Botulinum Toxin and Hyaluronic Acid Fillers, Complication Management following Rejuvenation Procedures with Hyaluronic Acid Fillersan Algorithm-based Approach, The Five-step Lower Blepharoplasty Technique Refined, Privacy Policy (Updated December 15, 2022). Depending on the location and quantity of these substances, surgery is performed under local or general anesthesia. 4 Jan 2017 5 months post Hi ladies.. Click on the procedure of your interest or contact us at no cost. Unicentro Torre Panamericana Centro Comercial Bocagrande Centro Mdico Nobel Its symptoms and consequences are hardening and deformations. This cross-sectional, descriptive observational study included 196 patients with biopolymers in buttocks, without a previous diagnosis of autoimmune disease and who were diagnosed with ASIA between January 1, 2017 and December 31, 2020 according to the 2011 criteria proposed by Shoenfeld and Agmon-Levin5,10patients with three major criteria, those with two major criteria and one minor criterion, or those with one major criterion and one minor criterion, with the essential major criterion being exposure to an adjuvant before the onset of symptoms. Further, the presence of multiple suspicious adjuvants to which the individual may be exposed make it difficult to establish a precise temporalcausal association. By making research easy to access, and puts the academic needs of the researchers before the business interests of publishers. 49C - 64 9 No. Bogot, Colombia, Cra 7Bis No. Silicone or biopolymer injections are removed surgically if a buildup of bulky material is under the skin. 5, the maximum biopolymer removal rates for the samples that could be achieved by a high dosage are plotted. Fate of biopolymer after pollutant removal. . If you are planning to come to Colombia for health tourism and need help, write to us, we will advise you. In this solution, the tests were carried out to know the adequate doses to treat the synthetic water prepared in the laboratory. 3. The turbidity results (Graph 2) showed that the best biopolymers to remove these solids associated with turbidity were Melocactus spp. Where have we come from? As a research group, considering the clinical and paraclinical characteristics before and after surgery, we suggest naming this condition human adjuvant disease caused by biopolymers. We also suggest defining patients with this condition as follows: patients with a history of having biopolymers in the previous 614 years who present one or more of the following symptoms: myalgia, arthralgia, asthenia, adynamia, and predominantly sensitive neurological symptoms, with positivity of any of the following: ANAs, complement protein C3 and C4, LDH, lupus anticoagulant, or rheumatoid factor and showing improvement on removal of the material. Medelln, Colombia, Outpatient consultation in general medicine, gynecology and obstetrics, Internal medicine, endocrinology, vascular surgery, nutrition and dietician, psychology, respiratory therapy, Calle 86 No. In the case of Opuntia sp., they are used to be present in the Colombian regions already named and sufficiently studied, in the same way Aloe vera and Aloe arborescens were selected (Figure3). Patients with uncontrolled diabetes mellitus and arterial hypertension; active infection at the site of biopolymer administration; human immunodeficiency virus infection; or a diagnosis of disseminated infiltration in the organ, device, or biopolymer system (stage V) were excluded.11,12 Thus, 190 patients were included in the study. They can migrate once infiltrated and reach areas on the face such as Lips, cheeks and neck. Its based on principles of collaboration, unobstructed discovery, and, most importantly, scientific progression. It is important to attend every post-surgery massage and control. This can be explained by the physiology of this acute phase reactant as it is produced by an anaerobic metabolic reaction secondary to cell lysis due to chronic inflammation, tissue damage, and production of free radicals by biopolymers. Thyroid surgery without scarring, . The removal of biopolymers using an open surgical technique in symptomatic or asymptomatic patients is crucial for functional and reconstructive purposes and to improve the quality of life.
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